Hiromu Sakurai
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A drug based on a chemical found in garlic can treat diabetes types
I and II when taken as a tablet, a study in the new Royal Society of
Chemistry journal Metallomics says. When Hiromu Sakurai and
colleagues from the Suzuka University of Medical Science, Japan, gave
the drug orally to type I diabetic mice, they found it reduced blood
glucose levels.
The drug is based on vanadium and allixin, a compound found in garlic, and its action described in an Advance Article from Metallomics available free online from today. The first issue of the new journal will be published in 2009.
In previous work they had discovered the vanadium-allixin compound
treated both diabetes types when injected, but this new study shows the
drug has promise as an oral treatment for the disease.
Type I diabetes (insulin dependent) is currently treated with daily
injections of insulin, while type II (non-insulin dependent) is treated
with drugs bearing undesirable side-effects – the authors note neither
treatment is ideal.
The researchers aim to test the drug in humans in future work.
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