HomeResources Cancer Research: Cancer research groups and their study focus
Cancer Research: Cancer research groups and their study focus
Faculty in cancer research and their research focus.
David M. Berman, M.D., Ph.D Assistant Professor of Pathology and Oncology Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University The Harry and Jeanette Weinberg Building, Suite 1100 401 North Broadway Baltimore, MD 21231 Phone: (443) 287-0878 e-mail:
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Study focuses on the roles of embryonic patterning pathways in the development and pathophsyiology of urogenital organs. The research group investigates the hypothesis that chronic injury leads to activation of these pathways in an effort to regenerate damaged tissue, and that cancers arise in repairative cells that become unable to return to the quiescent state. To study how particular signal transduction pathways contribute to these processes, the group studies experimental models of prostate and bladder regeneration and carcinogenesis and relate our findings to studies of human tissue.
G. Steven Bova, M.D. Institute of Genetic Medicine, Health Sciences Informatics, Oncology, and Urology Johns Hopkins University Phone: (410) 614-5957 e-mail:
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Study focus: clinical-genomic study of metastatic prostate cancer using a new web-based database tool. By integrating pertinent clinical data and well-collected genomic information in prostate cancer metastases, the aim is to understand differences in phenotype among patients with different cancers, and as a result to find novel diagnostic and drug targets. Great opportunities for students interested in the molecular biology of cancer, informatics, software development, and integration of clinical and molecular medicine are available.
Dr. Menashe Bar-Eli, Director Program in Cancer Biology Department of Cancer Biology, Unit 173 The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Boulevard Houston, Texas 77030 Phone: 713-794-4004
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Research interest is to study the molecular biology of melanoma metastasis. The molecular changes associated with the transition of melanoma cells from radial growth phase (RGP) to vertical growth phase (VGP, metastatic phenotype) are not very well defined.
David J. McConkey, Ph.D. Associate Professor of Cancer Biology Department of Cancer Biology, Unit 173 The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Boulevard Houston, Texas 77030 e-mail:
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Study focuses on identifying the biochemical mechanisms that regulate apoptosis in tumor cells. The research group is also investigating the roles of death receptors in bladder cancer progression and response to therapy. my laboratory is studying the role of cyclooxygenase-2 (COX-2) in the suppression of apoptosis and promotion of angiogenesis in pancreatic cancer cells.
Glenn Rosen, Ph.D Cancer Biology program Alway Building, Room M105-I Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305-5121 Phone: 650-724-6795 e-mail:
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Research interest is to examine apoptotic and cell cycle pathways in the lung with a focus on fibrotic lung disease and lung cancer. His group is also studying TGF beta signaling in lung cells which regulates myofibroblast differentiation and epithelia mesenchymal transition.
Guowei Fang, Ph.D. Cancer Biology program Alway Building, Room M105-I Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305-5121 Phone:(650) 725-2762 e-mail:
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Study focuses on the molecular and cellular mechanisms that control mitosis and cytokinesis in normal cells and their dysregulations that lead to aneuploidy and genomic instability in cancer cells.
Hilary Coller, PhD Department of Molecular Biology - Princeton University Washington Road, Princeton, NJ 08544-1014 USA Lewis Thomas Lab-149 Phone: 609-258-8466 e-mail:
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Study focuses on genomic approaches to gain insight into cell cycle control in normal tissues and cancer.
Olga Troyanskaya Department of Molecular Biology - Princeton University Washington Road, Princeton, NJ 08544-1014 USA Computer Science Bldg-204 Phone: 609-258-1749 e-mail:
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Research focus: combining computational methods with an experimental component in a unified effort to develop comprehensive descriptions of genetic systems of cellular controls, including those whose malfunctioning becomes the basis of genetic disorders, such as cancer, and others whose failure might produce developmental defects in model systems. The experimental component the study groups focuses on is S. cerevisiae (baker's yeast).
Research area: breast cancer genomics, breast tumor metabolic pathways, molecular differences between invasive ductal and invasive lobular breast carcinomas.
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