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By Caroline Kanaiza
What is Serine?
Serine is one of the non-essential amino acids
that make up protein. It is synthesized in the body. It exits in L-serine and D-serine forms.
Health benefits
Serine, even though a non-essential amino acid, provides
crucial health benefits. It plays roles in protein, fatty acid, genetic code
carriers (DNA and RNA) synthesis, and muscle build-up. Serine is a constituent in
the brain and protective covers of nerves. Therefore, serine is an
important amino acid for the proper functioning of the brain and nervous
system. Furthermore, serine boosts healthy immune system by aiding
the production of antibodies.
Serine is also a component of all cell membranes.
Additional serine’s health benefits come
indirectly through its effect on other biochemicals. For example, serine is
a precursor for the production of amino acids such as glycine, cystein, and tryptophan .
Tryptophan, necessary for the synthesis of serotonin and functioning of
neurotransmitters, is known to help relieve stress, anxiety and depression.
Serine Deficiency
Serine deficiency symptoms include slow or
delayed cognitive and physical skills (psychomotor retardation), seizures and
microcephaly. Microcephaly refers to health condition in which the head size is
smaller than normal and is caused by underdevelopment of the brain.
Serine Food Sources
A select list of dietary sources of serine are provided in the table below.
| Serine food source |
Serine content g/100 gram of food
portion |
| Soybeans, mature seeds, raw |
2.12 |
| Egg, yolk, raw, fresh |
1.33 |
| Lentils, raw |
1.29 |
| Peanuts, all types, raw |
1.27 |
| Cowpea, catjang, mature seeds, raw |
1.19 |
| Nuts, almonds |
1.01 |
| Egg, whole, raw, fresh |
0.97 |
| Chickpeas (garbanzo beans,
bengal gram), mature seeds, raw |
0.97 |
| Seeds, sesame butter, tahini,
from raw and stone ground kernels |
0.97 |
| Flax seed, raw |
0.97 |
| Nuts, walnuts, english |
0.93 |
| Salami, Italian, pork |
0.90 |
| Beef, round, top round,
separable lean and fat, trimmed to 1/8" fat, select, raw |
0.87 |
| Beef, top sirloin, separable
lean only, trimmed to 1/8" fat, choice, raw |
0.86 |
| Fish, salmon, pink, raw |
0.81 |
| Crustaceans, shrimp, mixed
species, raw |
0.80 |
| Egg, white, raw, fresh |
0.80 |
| Chicken, broilers or fryers,
thigh, meat only, raw |
0.68 |
| Chicken, broilers or fryers,
wing, meat and skin, raw |
0.66 |
| Sausage, Italian, pork, raw |
0.55 |
| Milk, sheep, fluid |
0.49 |
| Pork, fresh, separable fat,
raw |
0.26 |
| Hummus |
0.25 |
| Soy milk, fluid |
0.18 |
| Milk, goat, fluid |
0.18 |
| Milk, whole, 3.25% milkfat |
0.11 |
| Asparagus |
0.11 |
| Snap beans, green, raw |
0.10 |
| Milk, human, mature, fluid |
0.04 |
Serine data source: USDA National Nutrient Database for Standard Reference, Release 19 (2006).
References:
de
Koning TJ, Klomp
LW. 2004. Serine deficiency
syndromes. Curr Opin
Neurol. 2004 Apr;17(2):197-204.
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